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Through collaborative agreements, Best Practice has been able to conduct significant post-marketing safety and effectiveness studies utilizing databases in US managed care companies, State mental health systems, and non-US-based national health services.
Best Practice brings together diverse panels of experts to undertake innovative database research projects. In the area of health policy, we work at the intersection of public policy, clinical science, economics and statistics to assemble teams that address complex multi-factorial diseases and their policy ramifications. Best Practice brings together multidisciplinary teams to address critical policy questions, while being sensitive to valid economic and clinical issues.
These research projects often address issues related to pharmacoeconomics and profitability of certain drugs or classes of drugs. Pharmaceutical companies worry about the imposition of narrowly defined cost-driven restricted formularies that some states have turned to, as the states address shortfalls in Medicaid budgets. State Medicaid programs and mental health authorities look for cost-effective ways to advance patient care in the face of rapidly escalating pharmacy budgets.
Selected database analysis projects resulting in publication:
Goodwin FK, Fireman B, Simon GE, Hunkeler EM, Lee J, Revicki D. (2003). Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA, 290(11):1467-73.
Jaffe JH, Bloor R, Crome I, Carr M, Alam F, Simmons A, Meyer RE. A Post Marketing Study of Relative Abuse Liability of Hypnotic Sedative Drugs. Addiction, 2004 Feb; 99(2):165-73.
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